Course name: Medicinal Chemistry I
COURSE CONTENT
General principles of Medicinal Chemistry
Rational discovery & development of drug molecules
Drug-receptor interactions
Quantitative structure-activity relationships
Combinatorial chemistry
Drug metabolism
Antitumor drugs:
- - antimetabolites
- - nucleic acid damaging agents
- - cell replication interfering agents
Antiviral dugs:
- - cell entry inhibitors
- - viral nucleic acid replication and translation inhibitors
- - late stage replication inhibitors
Antimicrobial drugs:
- - antimetabolites
- - bacterial wall assembly inhibitors
- - protein biosynthesis inhibitors
Antimicobacterial agents
Non steroidal anti-inflammatory agents
Antirheumatic drugs
Biotech drugs
LEARNING OUTCOME
Aim of this course is teaching the student the basic principles and knowledge on medicinal chemistry, drug discovery and development and drug metabolism. In addition, the student will get acquainted with the major classes of chemotherapeutic (anticancer, antiviral, antibacterial) and anti-inflammatory agents.
CREDITS: 8
CONTACT INFORMATION
Manlio Palumbo
Department of Pharmaceutical Sciences
Via Francesco Marzolo 5
35131 Padova
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