Course name: Organic Chemistry II
COURSE CONTENT
Acid-base chemistry of carbonyl compounds. Inductive and resonance effects; keto-enol tautomerism; alpha halogenations and alkylation; active methylene compounds.
Nucleophilic addition reactions of enolate ions with carbonyl compounds. Aldol and Claisen condensation.
Nucleophilic addition to alpha-beta unsaturated carbonyl compounds. 1,2 vs 1,4 addition; Michael additions; tandem additions; organocuprates.
Heterocycles. Nomenclature; Alicyclic and aromatic heterocycles. Piridine, diazines, quinoline and isoquinolines, pyrrole, thiophene, furan, indole, benzothiphene, benzofuran, azoles.
LEARNING OUTCOME
Aim of the course is to complete and strengthen the basic knowledge of organic chemistry, introducing multi step synthesis and retro synthetic analysis.
CREDITS: 4
CONTACT INFORMATION
Giulia Licini
Dipartimento di Scienze Chimiche via Marzolo,1
35131 Padova, Italy
e-mail:
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