Rational Medicinal Chemistry
The course focuses on the molecular basis of target-based drug discovery, with emphasis on the biological targets of therapeutic relevance for rational discovery & development of small molecules drugs.
Topics covered through the course are:
Principles governing drug-receptor interactions, molecular mechanism of drug-receptor recognition, stereochemistry.
Discovery of Lead compounds, structure-activity relationships.
Rational development of drugs: natural products and existing drugs as chemical scaffolds for the discovery and design of novel therapeutics, analog design, computer-aided rational design, peptidomimetics.
Development of antibacterial and antiviral drugs.
CREDITS: 6
Barbara Gatto
Department of Pharmaceutical Sciences
University of Padova
Via Marzolo 5
35131 Padova
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