Course name: Methods in Pharmacology
COURSE CONTENT
EMEA and procedures to obtain marketing authorization for medicinal products (centralized procedure).
Preclinical studies to assess the efficacy and toxicity of new drugs. Mutagenesis, cancerogenesis, and teratogenesis: in vivo and in vitro experimental models. Relationships between animal experiments and clinical results.
In vitro assays in pharmacogenomic studies. Genetic polymorphisms of biotrasformation enzymes and P-glycoprotein transporter.
Cytofluorimetry and immunohystochemistry techniques: some applications to study the molecular mechanisms of drugs on cell cycle regulation in human cancer cell lines
LEARNING OUTCOME
Knowledge regarding in vivo and in vitro experimental models to evaluate the efficacy and the safety of drugs.
CREDITS : 4 CFU
CONTACT INFORMATION
Laura Caparrotta,
Associate Professor
University of Padova
Department of Pharmacology and Anaesthesiology
Largo E. Meneghetti 2
35131 Padova, Italy
tel. +39-049-8275090
fax +39-049-8275093
e-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it